The daughter of John Wagaman and Barbry Houser, Nancy was known as Anna. Her family moved to Monroe County, Indiana in the early 1830's, however, Anna's maternal grandfather died in Clermont County, Ohio in 1825. This may indicate that the Wagamans moved first to Ohio before everyone except Anna left for southern Indiana.

Anna married Emanuel Hoover on 23 Feb 1826 in Franklin Township, Clermont County, Ohio. They were the parents of 11 children.

Anna and Emanuel's daughter, Mary Anna "Mollie" Hoover, was married to George W. Vantine. He served in the Civil War from 16 Aug 1861 until his death from bronchitis at Benton Barracks, St. Louis, Missouri on 26 Jan 1865.

George Vantine was cited for "Distinguished Service" during the war, as was his younger brother, Daniel Vantine. Daniel served as a Union private with the 16th Regiment Kentucky Infantry, Company E. He later married his brother's widow, Mary Anna "Mollie" Hoover Vantine, after George's death during the war.

When she died in 1877, Anna was 70 years, 9 months and 6 days old. She was preceded in death by her husband, Emanuel, who passed away in 1873.

Children: 8 daughters, 3 sons.

Mother of:
Martha Ann Hoover Watson
Sarah Hoover Hendrixson
Elizabeth Hoover Watson
Gideon Walter Hoover
Joanna Hoover
Jacob Randolph Hoover
Saloma Jane Hoover Derrough
Mary Anna "Mollie" Hoover Vantine Vantine
John M. B. Hoover
Ervena Ellen Hoover Pangburn*
Amanda Hoover

Nancy Anna's siblings:
Elizabeth "Betsy" Wagaman Grow
Abraham Wagaman
Sarah Ann "Sally" Wagaman Trisler
Solomon Wagaman
Joshua Harrison Wagaman, Sr.
Susannah A. Wagaman Rohrer
Mary Wagaman Mitchell
David Wagaman
Martha Wagaman Bryant
John R. Wagaman
Catherine Wagaman Bales
Lucy Ann Wagaman Vint
Alice Ann Wagaman Franklin

*Ervena Hoover Pangburn's name also appears on a stone in Pennsylvania where her husband, John Pangburn, is buried. For some reason, she was interred in Champaign County, Illinois instead.