Alphee was the son of Donatien Domingues and Louisa Amelina Migues of Patoutville.
His siblings were Alfred Domingues,
Hirma Domingues (Hebert), Patoutville, LA
Dr. Polycarpe J. "Dr. P.J." Domingues, Kerrville, Texas
Honora Marie Domingues (Darby) Lake Charles
Felix Domingues,
Joseph Gaston Domingues,
and Gertrude Domingues (Schexnayder). Jeanerette

Alphe Domingues Sr. was married to Marguerite Hebert & had 8 children.
Their children were Alphe Noe Domingues Jr. (Gracious Romero),
Fernand Joseph Domingues (Marie Daisy Gary) of Port Arthur, Texas,
Marie Domingues (Harry Carlton "Harry" Bailey of Dallas, Texas),
Eda Marie Domingues (Alfred Bonin of Sulphur, LA),
Celina Domingues (Infant),
Twin brothers Ory Hypolite Domingues of Freeport (Remy Trosclair) and Ovey Polycarpe of Lake Jackson (Florence Ransonet),
and May Domingues of Sulphur, Louisiana (Harvey Ellender.) Marguerite died one year after the birth of May. At that time, May was adopted by Richard and Elizabeth Rodriguez Bourgeois and they had two other daughters.

His 2nd wife was Alida Hebert, who was living in the home with her grandmother as a helper to the family with 8 children. After the marriage to Alida, the couple had 12 more children.

The Children were Lloyd Louis Domingues,
Agnes Domingues Landry of Lake Jackson,
Evelyn Domingues Hebert,
Charles Domingues,
Clerfa Domingues of Port Arthur (Martha Blanchard),
Euclede Domingues,
Robert Joseph Domingues,
Twins including Clopha Domingues who lived on Grand Marais Road in the Patoutville, Jeanerette LA area,
and Clovis Domingues (Una Delahoussaye) of St. Martinville,
Aline Domingue Hebert on Grand Marais Road,
and Florine Marie Domingues Patout of Lydia was the baby of the family.