Thomas PARKER was born in 1814 in Georgia to:
• James PARKER Sr., who was born in North Carolina between 1780 and 1790 and died in 1843 in Screven County, &
• his first wife, whose name is unknown, who is believed to have been born in Georgia. James PARKER Sr. married secondly
• Elizabeth SASSER (born 1790-1800, died by 1848), and with his two wives James PARKER Sr. is thought to have had 22 children. Most of these children had large families of their own, and by 1880, there were many PARKERs farming their own land throughout the 80th District of Screven County. Thomas PARKER was a Justice of the Peace (J.P.) in 1843-1844.

Thomas PARKER's siblings were:
• James PARKER Jr. (1811-1888, a J.P. in 1864), who married Mary LEE (1816-1890) in 1833 in Screven County (by Rev. Moses Nathaniel MCCALL Sr.),
• John B. PARKER (about 1812-1840, a J.P. in 1833-1840), who married Priscilla NEWTON in 1834 in Screven County (by Rev. Mann DUTTON),
• Catharine PARKER (about 1813-1840), who first married Joseph LEE (born 1811-1813, brother of Mary LEE PARKER) in 1832 in Screven County (by Lewis M. STRICKLAND J.P. - their only child was Joseph Ann Elizabeth LEE COX COX, "Joanna" - widowed and remarried, she and her family settled in Alachua County, Florida), and then Edmund CAIL in 1834 in Screven County,
• Lemuel PARKER (1817-1883), who first married Eliza GRINER in 1840 in Screven County (by Lewis LEWIS J.P.), and then Cleary MINCY in 1854 in Screven County (by James HENDRICKS J.P.),
• Matthew PARKER (born about 1820, died by 1862), who married Martha WATERS in 1839 in Screven County (by Lewis LEWIS J.P.),
• Clarisa PARKER (1822-1892), who married Henry WATERS in 1838 in Screven County (by Lewis LEWIS J.P.),
• Gemima PARKER (1823-1887), who married William NEWTON in 1844 in Screven County (by Lewis LEWIS J.P.),
• Tabitha PARKER (1824-1898), who married William J. GRINER in 1842 in Screven County (by Lewis LEWIS J.P.),
• Jane PARKER (twin 1825-1895), who married Jonathan GRINER in 1844 in Screven County (by Lewis LEWIS J.P.),
• Hardy C. PARKER (twin born 1825, a J.P. in 1854), who married Sarah SCARBOROUGH in 1847 in Screven County (by Azariah ENNEIS),
• Mary Ann PARKER (1826-1885), who first married Jesse LEE in 1844 in Screven County (by brother Thomas PARKER J.P.), and then John W. MOORE in 1853,
• Eliza PARKER (born about 1829), who married William S. KEY in 1844 in Screven County (by brother Thomas PARKER J.P. - this couple moved to Florida),
• Henry PARKER (1833-1894, a J.P. in 1861-1864), who first married Martha Ann LEE in 1852 in Screven County (by Rev. Samuel SIMMONS), and then Margaret ZEIGLER in 1854 in Screven County (by Rev. Samuel SIMMONS),
• Elizabeth PARKER, "Betty" (born about 1834), who married Augustus DAUGHTRY in 1851 in Screven County (by Rev. Samuel SIMMONS), and
• three children, Benjamin, Sarah and Cinthey, who in died in 1843, and,
• four children whose names are not known, but who, by tradition are also thought to be children of James PARKER Sr., giving him a total of 22 sons and daughters.

Thomas PARKER was married in 1837 to Mary E. WATERS, and then in 1886 to Mrs. Freida FRIES STEIN.