Note: No death or burial record has been found for Susanna, and her death date is a rough approximation. Her birth year is a closer approximation, based on the 1586 baptism of her first child.

The provenance of Susanna is not known. She was married about 1585 to Edward Hutchinson, a mercer of Alford, Lincolnshire, England. She and Edward had eleven children together, all baptized in Alford from 1586 to 1607, nine of whom likely grew to maturity.

After becoming widowed, she left four grown children behind in England, and followed the other five to New England. In May 1636, at the age of around 70 years, she arrived in Boston with the family of her daughter Mary Wheelwright. She was admitted to the Boston church on 12 June 1636. The Wheelwrights lived in Boston proper upon their arrival in the colonies, but soon had property in Mount Wollaston, an area south of Boston that became the town of Quincy where Wheelwright preached. Almost immediately upon their arrival, Wheelwright became embroiled in the events of the Antinomian Controversy and was banished from the colony in November 1637.

While Wheelwright headed north to New Hampshire that winter, his family, including his mother-in-law Susanna, stayed at Mount Wollaston, waiting for spring before joining him. A year after arriving in Exeter, on 3 March 1638/9, Susanna was dismissed from the Boston church to her new church in Exeter. After living in Exeter for three or four years, Wheelwright was compelled to move again, and established a community at Wells, Maine by 1642, where he and his family lived until early 1647. It is here in Wells that Susanna died, and Noyes, Libby and Davis offer that she "may be the earliest born emigrant to die in Maine"

The preceding material is mostly from Noyes, Libby, and Davis, The Genealogical Dictionary of Maine and New Hampshire, p 367.