Cynthia Ann Pope lived in Louisville and married in 1828, Larz Anderson (1803-78)(Harvard 1822), son of Lt. Colonel Richard Clough (1750-1826) and Sarah Marshall Anderson (1779-1854), of Jefferson County, Ky. He was a lawyer, served in the Kentucky Legislature in 1833, and moved to Cincinnati in 1835. Their only child was Richard Clough Anderson III (1829-78). Larz Anderson's father, Lt. Colonel Richard Clough Anderson, was an aide to Gen. LaFayette during the Revolution. He moved to Kentucky in 1783, and represented Jefferson County in the Kentucky Legislature in 1812, 1814. About 1790, he built a home "Soldier’s Retreat" on 900 acres outside of Louisville. The house was destroyed by lightning in 1840 and in about 1986 was rebuilt at 9300 Seaton Springs Parkway. Nearby is a family cemetery and Colonel Anderson Parkway. Anderson County, Ky. was named in honor of Larz Anderson's brother, Richard Clough Anderson Jr. (1788-1826), who served in Congress, 1817-21, the Kentucky Legislature, 1815, 1821-22, where he was speaker in 1822, and was Minister to Colombia and Panama. Two other brothers were Lt. Governor Charles Anderson (1814-95), of Ohio, and General Robert Anderson (1805-71)(WestPoint 1825) who was in command of Fort Sumter in the Charleston Harbor when it was fired upon by Confederate General Beauregard's forces on April 12-13, 1861. Adjutant General Larz Anderson III (1866-1937)(Harvard 1888) built the magnificent mansion "Anderson House" in 1902-5, which he donated to, and houses, The Society of Cincinnati in Washington, D.C. He was U.S. minister to Belgium, 1911-12, and ambassador to Japan, 1912-13.

Cynthia Ann Pope died in 1829/30, and likely was buried in the Pope family cemetery behind 2116 Edgehill Road in Louisville. In 2014-15, the remains in the family cemetery were removed to the Kate Pope lot in Cave Hill Cemetery by archeologist Jay Stottman through the efforts of James H. Barr III.

See William Pope Jr. Will, 3 Will Book 370, Jefferson County, Ky.; W.P. Anderson, Anderson Family Records (Cincinnati, 1936), 56 (photos of Larz Anderson); William Barrow Floyd, Matthew Harris Jouett: Portraitist of the Ante-Bellum South (Transylvania Univ., 1980), 48 (contains picture of Jouett's painting of Cynthia Ann Pope. The painting is in the Dayton Art Institute); Samuel W. Thomas, The Architectural History of Louisville, 1778-1900 (Filson Historical Society, Louisville, 2009), 19 (picture of rebuilt "Soldier’s Retreat"); Donna M. Neary, Historic Jefferson County (Ky.) (Jefferson County Fiscal Court, Merrick Printing Co., 2000), 123 (photo of rebuilt "Soldier’s Retreat"); James Houston Barr III, Lt. Colonel Nathaniel Pope, c1610-1660, of Virginia, Ancestor of Washington, Governors and Legislators, History of His Descendants (Louisville, Ky. 2018), 365.