From Twentieth Century History of Clearfield County, Pennsylvania,
and Representative Citizens, by Roland D. Swoope, Jr.,
Chicago: Richmond-Arnold Publishing Company, 1911, page 374.

http://files.usgwarchives.net/pa/clearfield/bios/ake-n-f-k.txt

"N. F. K. AKE, M. D., physician and surgeon, at Curwensville, Pa., where he has been established in practice since the summer of 1897, is a member of an old Pennsylvania family of high standing. He was born August 11, 1873, at
Reynoldsville, Jefferson county, Pa., and is the only child of his parents, Samuel V. and Frances P. (Kelly) Ake. His father was a general merchant at Houtzdale, Pa., for a number of years. His great-grandfather once owned the land for many miles surrounding the present town of Williamsburg, Blair county, which was then called Akestown, in his honor.

N. F. K. Ake was afforded excellent educational advantages and is a graduate of Houtzdale High School and later from the Medico-Chirurgical College at Philadelphia in 1897. On August 3, 1897, he established himself in medical practice at Curwensville, where he has met with more than usual success. He is a member of a number of the leading medical societies and has served as medical examiner for numerous insurance organizations. Politically he is a Democrat.

Dr. Ake was married October 21, 1896, to Miss Bertha Biddle Carter, a daughter of William V. and Hannah E. (Biddle) Carter, of Philadelphia, and they have three children, Kenneth Whittier, Frances Lenore and Hannah Dorothy. Dr. Ake is a member of the Masonic fraternity."

[Note that this Samuel V Ake is likely not the same man as the Samuel VB Ake Pennsylvania 84th infantry during the Civil War of which Company E was of Blair Co. Pa. See https://familysearch.org/ark:/61903/1:1:KDPP-72R which shows this Samuel VB Ake's widow Lizze living in Indiana.]

Nicholas' wife Bertha and children Kenneth W and Francis L[enore] are at the home of her parents in the 1900 census:

Wm V Carter Head M 60 Pennsylvania
Hannah Carter Wife F 53 Pennsylvania
S Jane Carter Daughter F 25 Pennsylvania
Susie Carter Daughter F 11 Pennsylvania
Bertha Ake Daughter F 23 Pennsylvania
Kenneth W Ake Son-in-law M 3 Pennsylvania
Frances L Ake Daughter-in-law F 1 Pennsylvania

See: https://familysearch.org/ark:/61903/1:1:M3S8-TY7

Possibly Nicholas' automobile is parked in front of his doctor's office (between the two awnings) in this circa 1905 photo in Curwensville, PA:
http://www.usgwarchives.net/pa/clearfield/1picts/curwensville-150/071.htm

Nicholas K Ake, (Aike in Census) shows as age 6 in the 1880 Census residing in Houtzdale, Clearfield, Pennsylvania. His father Samuel V. B. Aike, born Pennsylvania, is age 35 so born approx. 1845 and Fannie Aike (born Maryland, probably as Francis Kelly) is age 34 in 1880, so born approx. 1846.
https://familysearch.org/ark:/61903/1:1:MWXP-41V

See the 1910 and 1920 census where he is living in Curwensville with his wife Bertha.
https://familysearch.org/ark:/61903/1:1:MGH5-JM8
https://familysearch.org/ark:/61903/1:1:MX92-TBW

In the month of September 1900, storms downed trees in the yard: "The two old trees that stood the storms of so many years and broke the force of the same from the Dr. Ake residence, gave way and succumbed to the high winds of last week.

Newspapers.com: Publication: Altoona Tribune Location: Altoona, Pennsylvania Issue Date: Wednesday, September 19, 1900, Page: Page 7

In January 1927 he is visiting Kane Pennsylvania for a severe allergy attack. "Dr. N. F. K. Ake, of Curwensville, who has been in this city for several weeks, seeking relief from a severe asthma attack; has fully recovered and returned home."

Newspapers.com: Publication: The Kane Republican i Location: Kane, PennsylvaniaIssue Date: Thursday, January 13, 1927, Page: Page 8

Possibly Nicholas Ake's grandfather was William Ake who has Samuel Ake and Rosa as son and daughter (theoretically William's father and aunt). See this newspaper notice: "Doctor N. Ake, of Curwensville, spent several days this week with his aunt, Mrs. R. S. Fluke, on Second street. Dr. Ake is the son of Samuel Ake, who was born and raised on the farm now owned by John B. Robinson. "

—Newspapers.com: Publication: Altoona Tribune Location: Altoona, Pennsylvania Issue Date: Saturday, August 31, 1907.

RS Fluke might be Rose S Fluke for which see:"Mrs. Rose Fluke is the wife of Mr. R. S. Fluke. We make the correction at the request of his friends." Newspapers.com: Publication: Altoona Tribune Location: Altoona, Pennsylvania, Wednesday, September 4, 1895.

Note: For William Ake who has Samuel Ake and Rosa as son and daughter see:

1850 US Census, Catharine Township, Blair, Pennsylvania

Name: William Ake
Event Type: Census
Event Year: 1850
Event Place: Catharine, Blair, Pennsylvania, United States
Gender: Male
Age: 33
Race: White
Race (Original):
Birth Year (Estimated): 1817
Birthplace: Pennsylvania
Household ID: 35
House Number: 34
Line Number: 41
Affiliate Name: The U.S. National Archives and Records Administration (NARA)
Affiliate Publication Number: M432
Affiliate Film Number: 755
GS Film Number: 20605
Digital Folder Number: 004191078
Image Number: 00257

Household Role Sex Age Birthplace
William Ake M 33 Pennsylvania
Susan M Ake F 23 Pennsylvania
Jan? I B Ake M 3 Pennsylvania [Saml based on succeeding census's]

Note: Could this image be read as say "Saml V.B. Ake" (see the V in Martin V. Ake line #11; see the Saml next page line 19..... initials in most lines followed by a period).

Citing this Record:
"United States Census, 1850," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:M442-5HH : 12 April 2016), William Ake, Catharine, Blair, Pennsylvania, United States; citing family 35, NARA microfilm publication M432 (Washington, D.C.: National Archives and Records Administration, n.d.).

1860 US Census, Catharine Township, Blair, Pennsylvania-

Wm H Ake M 42 [Blank]
Susan Ake F 33 [Blank]
Saml Ake M 12 [Blank]
Charles Ake M 10 [Blank]
Clara Ake F 6 [Blank]
Florence Ake F 5 [Blank]
Rosa Ake F 3 [Blank]

https://familysearch.org/ark:/61903/1:1:MXP3-BCB.

1870 US Census, ?Catharine Township, Blair, Pennsylvania

William Ake F 53 Pennsylvania
Susan Ake F 43 Pennsylvania
Charles Ake M 19 Pennsylvania
Clara Ake F 18 Pennsylvania
Florence Ake F 15 Pennsylvania
Rosa B Ake F 13 Pennsylvania
Williams Ake M 4 Pennsylvania
Ellen Hicks F 17 Pennsylvania

https://familysearch.org/ark:/61903/1:1:MZLP-MSH

1880 US Census, Catharine Township, Blair, Pennsylvania

Name: William H Ake
Event Type: Census
Event Date: 1880
Event Place: Catherine, Blair, Pennsylvania, United States
District: ED 163
Gender: Male
Age: 63
Marital Status: Married
Race: White
Race (Original): W
Occupation: Retired Farmer
Relationship to Head of Household: Self
Relationship to Head of Household (Original): Self
Birth Year (Estimated): 1817
Birthplace: Pennsylvania, United States
Father's Birthplace: Pennsylvania, United States
Mother's Birthplace: Pennsylvania, United States
Note:
Sheet Letter: B
Sheet Number: 275
Sheet Number and Letter: 275B
Household ID: 9560088
Person Number: 0
Volume: 1
Affiliate Name: The U.S. National Archives and Records Administration (NARA)
Affiliate Publication Number: T9
Affiliate Film Number: 1103
GS Film Number: 1255103
Digital Folder Number: 005162045
Image Number: 00114

Household Role Sex Age Birthplace
William H Ake Self M 63 Pennsylvania, United States
Susan Ake Wife F 53 Pennsylvania, United States
Florence Ake Daughter F 35 Pennsylvania, United States
William N Ake Son M 14 Pennsylvania, United States

Citing this Record:
"United States Census, 1880," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:MWXQ-MS8 : 16 July 2017), William H Ake, Catherine, Blair, Pennsylvania, United States; citing enumeration district ED 163, sheet 275B, NARA microfilm publication T9 (Washington D.C.: National Archives and Records Administration, n.d.), roll 1103; FHL microfilm 1,255,103.