Ann was the twelfth of twelve children born to James Owen "Jim" Murphree (1847-1923) and Lulu Smith (1853-1937). Seven of the children survived to adulthood; five died in infancy.

Ann was born in the house that her father built in 1881 on his share of the David Murphree estate. It was near "Point Evergreen," the house that her paternal grandfather, Judge David Murphree (1811-1866) had built (completed in 1848) on Prices Creek, near its intersection with the bend of the Guadalupe River between Cuero and Victoria. That area later became part of the Thomaston community which was established in 1872 upon the arrival of the Gulf, Western Texas and Pacific Railway's new extension from Victoria.

After Judge Murphree's death in 1866, Ann's father, James Owen Murphree (1847-1923) assumed responsibility for management of the family's ranch. After his marriage to Lulu Smith (1853-1939) on 27 Mar 1972, Jim and Lulu continued to live on that ranch and in that house where all 12 of their children were born.

In 1962, the book "A History of DeWitt County" by Nellie Murphree, Ann's older sister, was published. In that book, Nellie wrote:

"Ann, a retired registered graduate nurse, did professional work at Burns Hospital (1923-1934) and private nursing at Cuero and Victoria for many years."

Also in that book, Nellie wrote about her brother Bob, herself and Ann:

"He, Nellie and Ann live in the parental home and remain active in the Cuero Presbyterian Church."

[Note: the transcription shown below of the obituary for Ann Murphree was provided by Find A Grave contributor MYEY, #85871568]

Miss Ann Murphree

THOMASTON - Funeral services for Miss Ann Elizabeth Murphree, 74, will be held at 3 p.m. tomorrow in Freund Funeral Home in Cuero with burial in Thomaston Cemetery.
Miss Murphree died at 7:45a.m. yesterday in a Cuero hospital after a short illness. She was a lifelong resident here and a retired registered nurse. She is survived by a sister, Miss Nellie L. Murphree of Thomaston; and two brothers, R. L. Murphree of Thomaston and John O. Murphree of Inez.

Corpus Christi Times
Corpus Christi, Texas
Friday, April 9, 1971
Page 6-B